Home Help Word English Spanish French Russian German Italian Chinese (Trad.) Chinese (Simpl.) Portuguese Arabic Turkish Greek » Definition of " Painful " in English English Dictionary Results Painful Full of pain; causing uneasiness or distress, either physical or mental; afflictive; disquieting; distressing. a. Painful Requiring labor or toil; difficult; executed with laborious effort; as a painful service; a painful march. a. Painful Painstaking; careful; industrious. a.